Endocrine Abstracts

Cushing’s syndrome is a condition characterized by hypercortisolism (endogenous and exogenous) regardless of its etiology. Hypercortisolism caused by an adrenocorticotropin secreting pituitary adenoma is defined as Cushing’s disease. These tumors represent 10-12% of all pituitary adenomas. ACTH-secreting macroadenomas occur in only 4-23% of all patients with Cushing’s disease. We present the case of 56-year-old female patient with hypercortisolism and stigmata o...

AimDepression in diabetic patients is related to low quality of life, inadequate abiding by diabetes diet, physical activity and drug therapy.Aim of the stady is determine the presence of depression and its impact on the level of metabolic control of the disease; impact of structured education on the level of knowledge and HbA1c in patient with diabetes type 1 (T1D)MethodsThe study included 38 patients with T...

Introduction: Secondary failure (SF) of oral therapy in patients with type 2 diabetes is a common clinical phenomenon, which often puts the practitioner in a dilemma as to which therapeutic regimen to choose for continuing therapy. The dilemma primarily applies to patients in whom there is no clear clinical and biochemical evidence of significant insulin deficiency. This is precisely why there has been an increased interest in the use of short-term intermittent insulin therapy...

Introduction: Acromegaly is a chronic disease that occurs as a result of excessive growth hormone secretion, caused by somatotropin-secreting tumors of the pituitary gland in 98% of cases. The first line of treatment for these patients is operative via transsphenoidal approach, however, absolute remission is not achieved in 50% of patients and pharmacological therapy is indicated.Case report: We will present the case of a 43-year-old patient who was hosp...

Introduction: The diagnostic criteria of polycystic ovary syndrome (PCOS) are still under discussion and the hormonal parameters, including anti-Mullerian hormone range and hyperandrogenism, are not determined. Serum AMH level has been proposed as a surrogate marker for PCOM and could, therefore, be integrated in the diagnostic classifications for PCOS\. The aim of the present study was to characterize hormonal features of PCOS and to establish the most important hormonal para...

Background: Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to androgen excess in these women. Therefore, the aim of the present study was to examine the association of adiponectin levels and androgens in women with PCOS.Methods: A total of 60 women with PCOS who met the 2003 Rotterdam ...

Background: While a considerable body of literature exists detailing outcomes in patients with adrenocortical carcinoma (ACC), reports specifically addressing a cohort of patients with recurrent disease remain scarce. Therefore, the objective of this study was to evaluate treatment outcomes in patients with recurrent ACC.Methods: In our cohort of 55 patients who underwent R0/Rx tumor resection between 2011 and 2022, 18 individuals (33%) exhibited recurre...